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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RASGRF1 All Species: 5.15
Human Site: T973 Identified Species: 12.59
UniProt: Q13972 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13972 NP_722522.1 1275 145383 T973 K H S Q D F E T N D E L K C K
Chimpanzee Pan troglodytes XP_001153586 1273 145146 T971 K H S Q D F E T N D E L K C K
Rhesus Macaque Macaca mulatta XP_001108408 514 59608 S232 I I Q D Y I R S P H A D S M R
Dog Lupus familis XP_545892 1304 148017 V961 N D E L R C K V I S F L E E V
Cat Felis silvestris
Mouse Mus musculus P27671 1262 144083 V968 D D T L K Y R V I C F L E E V
Rat Rattus norvegicus P28818 1244 142649 C952 L L K Y K V I C F L E E V M H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510010 1242 141041 P959 L E E V L R D P D L L P Q E R
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A2CEA7 1244 141569 V950 N G E L K M G V I C L L E E V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001122143 690 76494 V408 D D R R R S S V S P R R I S G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780300 1211 137984 I924 K F S K N F E I N E G L R N R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 39.6 93.3 N.A. 83.4 83.1 N.A. 64.8 N.A. N.A. 65.3 N.A. N.A. 25.1 N.A. 48
Protein Similarity: 100 99.4 39.9 94.9 N.A. 90.3 90.3 N.A. 78.7 N.A. N.A. 78.4 N.A. N.A. 36.3 N.A. 65.5
P-Site Identity: 100 100 0 6.6 N.A. 6.6 6.6 N.A. 0 N.A. N.A. 6.6 N.A. N.A. 0 N.A. 40
P-Site Similarity: 100 100 13.3 20 N.A. 26.6 6.6 N.A. 26.6 N.A. N.A. 13.3 N.A. N.A. 13.3 N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % A
% Cys: 0 0 0 0 0 10 0 10 0 20 0 0 0 20 0 % C
% Asp: 20 30 0 10 20 0 10 0 10 20 0 10 0 0 0 % D
% Glu: 0 10 30 0 0 0 30 0 0 10 30 10 30 40 0 % E
% Phe: 0 10 0 0 0 30 0 0 10 0 20 0 0 0 0 % F
% Gly: 0 10 0 0 0 0 10 0 0 0 10 0 0 0 10 % G
% His: 0 20 0 0 0 0 0 0 0 10 0 0 0 0 10 % H
% Ile: 10 10 0 0 0 10 10 10 30 0 0 0 10 0 0 % I
% Lys: 30 0 10 10 30 0 10 0 0 0 0 0 20 0 20 % K
% Leu: 20 10 0 30 10 0 0 0 0 20 20 60 0 0 0 % L
% Met: 0 0 0 0 0 10 0 0 0 0 0 0 0 20 0 % M
% Asn: 20 0 0 0 10 0 0 0 30 0 0 0 0 10 0 % N
% Pro: 0 0 0 0 0 0 0 10 10 10 0 10 0 0 0 % P
% Gln: 0 0 10 20 0 0 0 0 0 0 0 0 10 0 0 % Q
% Arg: 0 0 10 10 20 10 20 0 0 0 10 10 10 0 30 % R
% Ser: 0 0 30 0 0 10 10 10 10 10 0 0 10 10 0 % S
% Thr: 0 0 10 0 0 0 0 20 0 0 0 0 0 0 0 % T
% Val: 0 0 0 10 0 10 0 40 0 0 0 0 10 0 30 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 10 10 10 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _